It is unknown how Ghazan and Ming-Hua first met, but they were both in the Red Lotus together. They were both involved in a plan to capture Avatar Korra which failed and caused them to be imprisoned separately for thirteen years. Eventually, Zaheer escaped and rescued Ghazan. They both worked together to save Ming-Hua afterwards. Ming-Hua told Ghazan and Zaheer that she was not sure if she would ever see their ugly mugs again and Ghazan sarcastically replied that it was nice to see her to. They later worked together to bust P'Li out of her prison.
Ghazan and Ming-Hua later worked together on multiple attempts to capture Korra. Eventually, Zaheer sent them to capture Korra while she was in the Spirit World. Both worked together to fight and capture Mako and Bolin. Korra was captured by the forces of the Earth Queen instead so they went to Ba Sing Se with their prisoners. While on their way, Bolin decided to make up stories about Ghazan and guessed that there was an unspoken attraction between him and Ming-Hua. Ghazan was impressed and said that two of the three stories he made up were correct.
Ghazan and Ming-Hua later worked together during the battle at the Northern Air Temple. Ghazan led Mako, Bolin and Asami to Tenzin while Ming-Hua set up fake airbenders with her waterbending. Ghazan started to fight them until Ming-Hua told him to just bury them so they could leave. They later took off in an airship together and witnessed Zaheer flying. Eventually, the Red Lotus managed to poison Korra and force her into the Avatar State so that they could kill her. Ming-Hua and Ghazan worked together to try and kill her until Mako and Bolin arrived to fight them. Mako managed to kill Ming-Hua and Ghazan decided to commit suicide in an attempt to bring them down with him.
Mingzan is a fairly popular Red Lotus ship. Some just ship the two together so that the members of the Red Lotus can be shipped with each other, but the pairing became popular after Bolin suggested that there might be an attraction between the two. When Mako joined Bolin against Ghazan, some speculated that he may have figured out that Ming-Hua was dead and was upset about it which was partially the reason why he committed suicide. A lot of fans feel that they are a great match because they always seem to work well together. In fan fiction, Ghazan and Ming-Hua were often portrayed as having a relationship before their imprisonment.
- The creators themselves have stated that they are not sure if Bolin was right about there being an attraction between Ghazan and Ming-Hua.