When Sakura talked to Hinata in the bath house, she asked if she and Menma had anything going on. They first met when Menma went to Konoha to steal a scroll and managed to beat everybody, including his parents, Tsunade, and Sakura. Sakura was also kidnapped by Menma. However, he later attempted to extract Kurama from Naruto so Sakura attempted to punch him and interrupt the process.
MenSaku has a decent amount of popularity in the Naruto fandom. It is considered to be an alternate universe counterpart to NaruSaku and is commonly shipped by fans of that ship. Many ship Menma with the Sakura of his universe while some ship him with the main universe Sakura. MenSaku usually rivals the MenmaHina pairing as well as NaruHina and occasionally NaruSaku if the main universe Sakura is involved.
- The Sakura of Menma's universe actively competes against Hinata for his affection and blushes at him.
- In the drama Road to Ninja CD Drama: Road to Charasuke, many of the girls became shocked when main universe Sakura said that there was nothing between her and Menma, suggesting that the two are very close in the alternative universe.
- In the Road to Ninja movie when main universe Naruto is upset Minato asks him if something happened between him and Sakura, suggesting that the alternative Naruto and Sakura are close.
- In Road to Ninja Kushina teases Naruto about wanting to "look good" in front of Sakura. This may imply that Menma also had feelings for Sakura in the alternative world.